Tyrosines 868, 966, and 972 in the Kinase Domain of JAK2 Are Autophosphorylated and Required for Maximal JAK2 Kinase Activity-Reference-Cited by-同舟云学术

Tyrosines 868, 966, and 972 in the Kinase Domain of JAK2 Are Autophosphorylated and Required for Maximal JAK2 Kinase Activity

Published:2010-05-01 Issue:5 Volume:24 Page:1062-1076
ISSN:0888-8809
Container-title:Molecular Endocrinology
language:en
Short-container-title:

Author:

Argetsinger Lawrence S.¹,Stuckey Jeanne A.²,Robertson Scott A.³,Koleva Rositsa I.⁴,Cline Joel M.¹,Marto Jarrod A.⁴,Myers Martin G.³,Carter-Su Christin¹

Affiliation:

1. Department of Molecular and Integrative Physiology (L.S.A., J.M.C., C.C.-S.), University of Michigan Medical School, Ann Arbor, Michigan 48109-0662

2. Department of Biological Chemistry (J.A.S.), University of Michigan Medical School, and Life Sciences Institute, University of Michigan, Ann Arbor, Michigan 48109-2216

3. Departments of Internal Medicine and Molecular and Integrative Physiology (S.A.R., M.G.M.), University of Michigan Medical School, Ann Arbor, Michigan 48109-5638

4. Department of Cancer Biology (R.I.K., J.A.M.), Dana-Farber Cancer Institute and Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115-6084

Publisher

The Endocrine Society

Subject

Endocrinology,Molecular Biology,General Medicine

Link

http://academic.oup.com/mend/article-pdf/24/5/1062/8944172/mend1062.pdf

Reference56 articles.

1. Mechanism of signaling by growth hormone receptor.;Argetsinger;Physiol Rev,1996

2. Direct stimulation of Jak/STAT pathway by the angiotensin II AT1 receptor.;Marrero;Nature,1995

3. Rho family GTPases are required for activation of Jak/STAT signaling by G protein-coupled receptors.;Pelletier;Mol Cell Biol,2003

4. Activation of Jak2 catalytic activity requires phosphorylation of Y1007 in the kinase activation loop.;Feng;Mol Cell Biol,1997

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