N-Oleoyldopamine Enhances Glucose Homeostasis through the Activation of GPR119
Author:
Affiliation:
1. Arena Pharmaceuticals, San Diego, California 92121
Publisher
The Endocrine Society
Subject
Endocrinology,Molecular Biology,General Medicine
Link
http://academic.oup.com/mend/article-pdf/24/1/161/10735565/mend0161.pdf
Reference44 articles.
1. A role for β-cell-expressed G protein-coupled receptor 119 in glycemic control by enhancing glucose-dependent insulin release.;Chu;Endocrinology,2007
2. A role for intestinal endocrine cell-expressed g protein-coupled receptor 119 in glycemic control by enhancing glucagon-like peptide-1 and glucose-dependent insulinotropic peptide release.;Chu;Endocrinology,2008
3. GPR119 is essential for oleoylethanolamide-induced glucagon-like peptide-1 secretion from the intestinal enteroendocrine L-cell.;Lauffer;Diabetes,2009
4. Discovery of the first potent and orally efficacious agonist of the orphan G-protein coupled receptor 119.;Semple;J Med Chem,2008
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