Defective Retinoic Acid Regulation of the Pit-1 Gene Enhancer: A Novel Mechanism of Combined Pituitary Hormone Deficiency
Author:
Affiliation:
1. Divisions of Endocrinology Departments of Medicine Children’s Hospital (L.E.C., K.Z., T.B., S.R.), Massachusetts 02115
2. Beth Israel Deaconess Medical Center (F.E.W.), Harvard Medical School Boston, Massachusetts 02115
Publisher
The Endocrine Society
Subject
Endocrinology,Molecular Biology,General Medicine
Link
http://academic.oup.com/mend/article-pdf/13/3/476/10714339/mend0476.pdf
Reference33 articles.
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2. Dissection of functional domains of the pituitary-specific transcription factor GHF-1.;Theill;Nature,1989
3. The POU-specific domain of Pit-1 is essential for sequence-specific, high affinity DNA binding and DNA-dependent Pit-1-Pit-1 interactions.;Ingraham;Cell,1990
4. Activation of cell-specific expression of rat growth hormone and prolactin genes by a common transcription factor.;Nelson;Science,1988
5. A pituitary POU domain protein, Pit-1, activates both growth hormone and prolactin promoters transcriptionally.;Mangalam;Genes Dev,1989
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