Distinguishing Androgen Receptor Agonists and Antagonists: Distinct Mechanisms of Activation by Medroxyprogesterone Acetate and Dihydrotestosterone-Reference-Cited by-同舟云学术

Distinguishing Androgen Receptor Agonists and Antagonists: Distinct Mechanisms of Activation by Medroxyprogesterone Acetate and Dihydrotestosterone

Published:1999-03-01 Issue:3 Volume:13 Page:440-454
ISSN:0888-8809
Container-title:Molecular Endocrinology
language:en
Short-container-title:

Author:

Kemppainen Jon A.¹,Langley Elizabeth¹²,Wong Choi-iok¹,Bobseine Kathy³,Kelce William R.³,Wilson Elizabeth M.¹²

Affiliation:

1. Laboratories for Reproductive Biology and the Departments of Pediatrics (J.A.K., E.L., C-i.W., E.M.W.), University of North Carolina Chapel Hill North Carolina 27599

2. Biochemistry and Biophysics (E.L., E.M.W.) University of North Carolina Chapel Hill North Carolina 27599

3. Endocrinology Branch (K.B., W.R.K.) Reproductive Toxicology Division National Health and Environmental Effects Research Laboratory United States Environmental Protection Agency Research Triangle Park, North Carolina 27711

Publisher

The Endocrine Society

Subject

Endocrinology,Molecular Biology,General Medicine

Link

http://academic.oup.com/mend/article-pdf/13/3/440/10714135/mend0440.pdf

Reference67 articles.

1. Persistent DDT metabolite p,p′-DDE is a potent androgen receptor antagonist.;Kelce;Nature,1995

2. Environmental antiandrogens: developmental effects, molecular mechanisms and clinical implications.;Kelce;J Mol Med,1997

3. Carcinoma of the prostate.;Gittes;N Engl J Med,1991

4. Evidence for an anti-parallel orientation of the ligand-activated human androgen receptor dimer.;Langley;J Biol Chem,1995

5. Ligand-dependent, transcriptionally productive association of the amino- and carboxyl-terminal regions of a steroid hormone nuclear receptor.;Kraus;Proc Natl Acad Sci USA,1995

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