Estrogen Modulates Metabolic Pathway Adaptation to Available Glucose in Breast Cancer Cells

Author:

O'Mahony Fiona12,Razandi Mahnaz1,Pedram Ali1,Harvey Brian J.2,Levin Ellis R.134

Affiliation:

1. Division of Endocrinology, Department of Veterans Affairs Medical Center, Long Beach, California 90822; Departments of Medicine (F.O.,A.P., E.R.L.), University of California, Irvine, Irvine, California 92717

2. Department of Molecular Medicine (F.O., B.J.H.), Royal College of Surgeons in Ireland, Dublin 9, Ireland

3. Biochemistry (E.R.L.), University of California, Irvine, Irvine, California 92717

4. Pharmacology (E.R.L.), University of California, Irvine, Irvine, California 92717

Publisher

The Endocrine Society

Subject

Endocrinology,Molecular Biology,General Medicine

Reference31 articles.

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2. Ueber den Stoffwechsel der Tumoren; Biochemische Zeitschrift, 152; 319–344. Reprinted in English in the book on metabolism of tumors by O. Warburg;Warburg,1924

3. Understanding the Warburg effect: the metabolic requirements of cell proliferation.;Vander Heiden;Science,2009

4. Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis.;DeBerardinis;Proc Natl Acad Sci USA,2007

5. Blood supply, oxygenation status and metabolic micromilieu of breast cancers: characterization and therapeutic relevance.;Vaupel;Int J Oncol,2000

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