SH2B1—The Adaptor Protein that Could
Author:
Affiliation:
1. Departments of Medicine and Neuroscience, Albert Einstein College of Medicine, Bronx, New York 10461
Publisher
The Endocrine Society
Subject
Endocrinology
Link
http://academic.oup.com/endo/article-pdf/151/9/4100/9009051/endo4100.pdf
Reference22 articles.
1. Identification of SH2-Bβ as a substrate of the tyrosine kinase JAK2 involved in growth hormone signaling.;Rui;Mol Cell Biol,1997
2. Cloning and characterization of APS, an adaptor molecule containing PH and SH2 domains that is tyrosine phosphorylated upon B-cell receptor stimulation.;Yokouchi;Oncogene,1997
3. Cloning and characterization of Lnk, a signal transduction protein that links T-cell receptor activation signal to phospholipase Cγ1, Grb2, and phosphatidylinositol 3-kinase.;Huang;Proc Natl Acad Sci USA,1995
4. The Shb adaptor protein binds to tyrosine 766 in the FGFR-1 and regulates the Ras/MEK/MAPK pathway via FRS2 phosphorylation in endothelial cells.;Cross;Mol Biol Cell,2002
5. SH2-Bα is an insulin-receptor adapter protein and substrate that interacts with the activation loop of the insulin-receptor kinase;Kotani;Biochem J,1998
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