Critical Residues for the Specificity of Cofactors and Substrates in Human Estrogenic 17β-Hydroxysteroid Dehydrogenase 1: Variants Designed from the Three-Dimensional Structure of the Enzyme-Reference-Cited by-同舟云学术

Critical Residues for the Specificity of Cofactors and Substrates in Human Estrogenic 17β-Hydroxysteroid Dehydrogenase 1: Variants Designed from the Three-Dimensional Structure of the Enzyme

Published:2001-11-01 Issue:11 Volume:15 Page:2010-2020
ISSN:0888-8809
Container-title:Molecular Endocrinology
language:en
Short-container-title:

Author:

Huang Yi-Wei¹,Pineau Isabelle¹,Chang Ho-Jin¹,Azzi Arezki¹,Bellemare Véronique¹,Laberge Serge¹,Lin Sheng-Xiang¹

Affiliation:

1. Medical Research Council Group in Molecular Endocrinology, Oncology, and Molecular Endocrinology Research Center, Laval University Medical Center, Québec, Québec G1V 4G2, Canada

Publisher

The Endocrine Society

Subject

Endocrinology,Molecular Biology,General Medicine

Link

http://academic.oup.com/mend/article-pdf/15/11/2010/8950322/mend2010.pdf

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3. Stimulation of cell proliferation and estrogenic response by adrenal C19-δ 5-steroids in the ZR-75–1 human breast cancer cell line.;Poulin;Cancer Res,1986

4. Growth control of human mammary cancer cells (MCF-7 cells) in culture: effect of estradiol and growth factors in serum-containing medium.;Aakvaag;Cancer Res,1990

5. In situ aromatization enhances breast tumor estradiol levels and cellular proliferation.;Yue;Cancer Res,1998

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