1. Institute of Biomedical Research (S.R.J., A.M.R., C.J.M., J.A.F., R.S.B.), School of Clinical and Experimental Medicine, University of Birmingham, Birmingham B15 2TH, United Kingdom
2. Department of Cardiothoracic Surgery (A.M.R., R.V., R.S.B.), University Hospitals Birmingham, National Health Service Foundation Trust, Birmingham B15 2TH, United Kingdom