1. School of Clinical and Experimental Medicine (K.B., B.T., J.A.F.), College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, United Kingdom
2. College of Medical and Dental Sciences, Institute of Biomedical Research, and School of Health and Population Sciences (R.L.H.), College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, United Kingdom