Variable Degree of Growth Hormone (GH) and Insulin-Like Growth Factor (IGF) Sensitivity in Children with Idiopathic Short Stature Compared with GH-Deficient Patients: Evidence from an IGF-Based Dosing Study of Short Children-Reference-Cited by-同舟云学术

Variable Degree of Growth Hormone (GH) and Insulin-Like Growth Factor (IGF) Sensitivity in Children with Idiopathic Short Stature Compared with GH-Deficient Patients: Evidence from an IGF-Based Dosing Study of Short Children

Published:2010-05-01 Issue:5 Volume:95 Page:2089-2098
ISSN:0021-972X
Container-title:The Journal of Clinical Endocrinology & Metabolism
language:en
Short-container-title:

Author:

Cohen Pinchas¹,Germak John²,Rogol Alan D.³,Weng Wayne²,Kappelgaard Anne-Marie⁴,Rosenfeld Ron G.⁵,

Affiliation:

1. Department of Pediatric Endocrinology (P.C.), Mattel Children’s Hospital at University of California, Los Angeles, Los Angeles, California 90095

2. Clinical Development, Medical, and Regulatory Affairs (J.G., W.W.), Novo Nordisk Inc., Princeton, New Jersey 08540

3. Department of Pediatrics (A.D.R.), Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, Indiana 46202, and University of Virginia, Charlottesville, Virginia 22908

4. Scientific Marketing GHT (A.-M.K.), Novo Nordisk A/S, Virum, Denmark DK-2830

5. Department of Pediatrics (R.G.R.), Oregon Health and Science University, Portland, Oregon 97239

Publisher

The Endocrine Society

Subject

Biochemistry (medical),Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism

Link

http://academic.oup.com/jcem/article-pdf/95/5/2089/9066979/jcem2089.pdf

Reference30 articles.

1. A dose-response curve for human growth hormone;Frasier;J Clin Endocrinol Metab,1981

2. Dose-response study of biosynthetic human growth hormone (GH) in GH-deficient children: effects on auxological and biochemical parameters. Dutch Growth Hormone Working Group;de Muinck Keizer-Schrama;J Clin Endocrinol Metab,1992

3. High dose recombinant human growth hormone (GH) treatment of GH-deficient patients in puberty increases near-final height: a randomized, multicenter trial. Genentech, Inc., Cooperative Study Group;Mauras;J Clin Endocrinol Metab,2000

4. Effects of dose and gender on the growth and growth factor response to GH in GH-deficient children: Implications for efficacy and safety;Cohen;J Clin Endocrinol Metab,2002

5. Height velocity targets from NCGS for first year growth hormone responses in short children;Bakker;J Clin Endocrinol Metab,2008

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