Pegylated Long-Acting Human Growth Hormone Is Well-Tolerated in Healthy Subjects and Possesses a Potential Once-Weekly Pharmacokinetic and Pharmacodynamic Treatment Profile-Reference-Cited by-同舟云学术

Pegylated Long-Acting Human Growth Hormone Is Well-Tolerated in Healthy Subjects and Possesses a Potential Once-Weekly Pharmacokinetic and Pharmacodynamic Treatment Profile

Published:2010-07-01 Issue:7 Volume:95 Page:3411-3417
ISSN:0021-972X
Container-title:The Journal of Clinical Endocrinology & Metabolism
language:en
Short-container-title:

Author:

Rasmussen Michael Højby¹,Bysted Britta V.²,Anderson Thomas W.³,Klitgaard Thomas⁴,Madsen Jesper⁵

Affiliation:

1. Departments of Medical and Science (M.H.R.), Novo Nordisk A/S, DK 2880 Bagsværd, Denmark

2. Clinical Pharmacology (B.V.B.), Novo Nordisk A/S, DK 2880 Bagsværd, Denmark

3. Development Drug Metabolism & Pharmacokinetics (T.W.A.), Novo Nordisk A/S, DK 2880 Bagsværd, Denmark

4. Clinical Pharmacology–Biomodelling (T.K.), Novo Nordisk A/S, DK 2880 Bagsværd, Denmark

5. Biostatistics (J.M.), Novo Nordisk A/S, DK 2880 Bagsværd, Denmark

Publisher

The Endocrine Society

Subject

Biochemistry, medical,Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism

Link

http://academic.oup.com/jcem/article-pdf/95/7/3411/9068691/jcem3411.pdf

Reference18 articles.

1. Growth hormone deficiency in children.;Richmond;Pituitary,2008

2. Evaluation and treatment of adult growth hormone deficiency: an Endocrine Society Clinical Practice Guideline.;Molitch;J Clin Endocrinol Metab,2006

3. Pegylation of somaropin (recombinant human growth hormone): impact on its clearance in humans.;Webster;Xenobiotica,2008

4. Weekly subcutaneous pegylated recombinant native human leptin (PEG-OB) administration in obese men.;Hukshorn;J Clin Endocrinol Metab,2000

5. Efficacy and safety of pegylated (40-kd) interferon α-2a compared with interferon α-2a in noncirrhotic patients with chronic hepatitis C.;Reddy;Hepatology,2001

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