Secretory Type II Phospholipase A2 Is Produced and Secreted by Epicardial Adipose Tissue and Overexpressed in Patients with Coronary Artery Disease

Author:

Dutour Anne12,Achard Vincent134,Sell Henrike5,Naour Nadia34,Collart Frederic6,Gaborit Benedicte12,Silaghi Alina1,Eckel Juergen5,Alessi Marie-Christine1,Henegar Corneliu347,Clément Karine347

Affiliation:

1. Institut National de la Santé et de la Recherche Médicale (A.D., V.A., B.G., A.S., M.-C.A.), La Timone Hospital, 13385 Marseille, France

2. Unité 626, Université de la Méditerranée, Assistance Publique-Hôpitaux de Marseille, Endocrinology Department North Hospital (A.D., B.G.), La Timone Hospital, 13385 Marseille, France

3. Institut National de la Santé et de la Recherche Médicale (V.A., N.N., C.H., K.C.), Unité 872, Nutriomique, F-75006 Paris, France

4. University Pierre et Marie Curie Paris 6 (V.A., N.N., C.H., K.C.), Centre de Recherche des Cordeliers, UMR S 872 F-75005 Paris, France

5. Institute of Clinical Biochemistry and Pathobiochemistry (H.S., J.E.), German Diabetes Center, 40225 Dusseldorf, Germany

6. Department of Cardiac Surgery (F.C.), La Timone Hospital, 13385 Marseille, France

7. Assistance Publique-Hôpitaux de Paris (C.H., K.C.), Pitié Salpetriere Hospital, Endocrinology, and Nutrition Department F-75013 Paris, France

Publisher

The Endocrine Society

Subject

Biochemistry (medical),Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism

Reference20 articles.

1. Epicardial adipose tissue extent: relationship with age, body fat distribution, and coronaropathy. Obesity (Silver Spring;Silaghi;Md),2008

2. Pericardial adipose tissue determined by dual source CT is a risk factor for coronary atherosclerosis;Greif;Arterioscler Thromb Vasc Biol,2009

3. Weight of pericardial fat on coronaropathy;Clément;Arterioscler Thromb Vasc Biol,2009

4. Human epicardial adipose tissue is a source of inflammatory mediators;Mazurek;Circulation,2003

5. Epicardial adipose tissue as a source of nuclear factor-κB and c-Jun N-terminal kinase mediated inflammation in patients with coronary artery disease;Baker;J Clin Endocrinol Metab,2009

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