Dysregulation of Glycogen Synthase COOH- and NH2-Terminal Phosphorylation by Insulin in Obesity and Type 2 Diabetes Mellitus-Reference-Cited by-同舟云学术

Dysregulation of Glycogen Synthase COOH- and NH2-Terminal Phosphorylation by Insulin in Obesity and Type 2 Diabetes Mellitus

Published:2009-11-01 Issue:11 Volume:94 Page:4547-4556
ISSN:0021-972X
Container-title:The Journal of Clinical Endocrinology & Metabolism
language:en
Short-container-title:

Author:

Højlund Kurt¹,Birk Jesper B.²,Klein Ditte K.²,Levin Klaus¹,Rose Adam J.²,Hansen Bo F.³,Nielsen Jakob N.²,Beck-Nielsen Henning¹,Wojtaszewski Jørgen F. P.²

Affiliation:

1. Diabetes Research Centre (K.H., K.L., H.B.-N.), University of Southern Denmark and Department of Endocrinology, Odense University Hospital, DK-5230 Odense, Denmark

2. Copenhagen Muscle Research Centre (J.B.B., D.K.K., A.J.R., J.N.N., J.F.P.W.), Molecular Physiology Group, Section of Human Physiology, Department of Exercise and Sport Sciences, University of Copenhagen, DK-2100 Copenhagen, Denmark

3. Diabetes Biology (B.F.H.), Novo Nordisk, DK-2760 Maalev, Denmark

Publisher

The Endocrine Society

Subject

Biochemistry, medical,Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism

Link

http://academic.oup.com/jcem/article-pdf/94/11/4547/9061094/jcem4547.pdf

Reference40 articles.

1. Increased phosphorylation of skeletal muscle glycogen synthase at NH2-terminal sites during physiological hyperinsulinemia in type 2 diabetes.;Højlund;Diabetes,2003

2. Hyperglycemia normalizes insulin-stimulated skeletal muscle glucose oxidation and storage in noninsulin-dependent diabetes mellitus.;Kelley;J Clin Invest,1990

3. Intracellular glucose oxidation and glycogen synthase activity are reduced in non-insulin-dependent (type II) diabetes independent of impaired glucose uptake.;Thorburn;J Clin Invest,1990

4. Reduced glycogen synthase activity in skeletal muscle from obese patients with and without type 2 (non-insulin-dependent) diabetes mellitus.;Damsbo;Diabetologia,1991