ROS Signaling by NOX4 Drives Fibroblast-to-Myofibroblast Differentiation in the Diseased Prostatic Stroma

Author:

Sampson Natalie1,Koziel Rafal1,Zenzmaier Christoph1,Bubendorf Lukas2,Plas Eugen3,Jansen-Dürr Pidder1,Berger Peter1

Affiliation:

1. Institute of Biomedical Aging Research (N.S., R.K., C.Z., P.J.-D., P.B.), Austrian Academy of Science, A6020 Innsbruck, Austria;

2. Institute of Pathology (L.B.), University Hospital Basel, CH4031 Basel, Switzerland;

3. Ludwig Boltzmann Institute for Andrology and Urology (E.P.), Hospital Lainz, A1130 Vienna, Austria

Publisher

The Endocrine Society

Subject

Endocrinology,Molecular Biology,General Medicine

Reference60 articles.

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2. Etiology of benign prostatic hyperplasia.;Isaacs;Eur Urol,1994

3. Cancer statistics, 2006.;Jemal;CA Cancer J Clin,2006

4. Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium.;Olumi;Cancer Res,1999

5. A system for studying epithelial-stromal interactions reveals distinct inductive abilities of stromal cells from benign prostatic hyperplasia and prostate cancer.;Barclay;Endocrinology,2005

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