The Critical Role of Shc in Insulin-Like Growth Factor-I-Mediated Mitogenesis and Differentiation in 3T3-L1 Preadipocytes

Author:

Boney Charlotte M.1,Gruppuso Philip A.1,Faris Ronald A.12,Frackelton A. Raymond1

Affiliation:

1. Department of Pediatrics Rhode Island Hospital (C.M.B., P.A.G., R.A.F.) Providence, Rhode Island 02903

2. Department of Medicine (A.R.F.) Roger Williams Hospital Providence, Rhode Island 02908. Departments of Pediatrics and Pathology and Laboratory Medicine Brown University Providence, Rhode Island 02906

Publisher

The Endocrine Society

Subject

Endocrinology,Molecular Biology,General Medicine

Reference52 articles.

1. IGF-I: a mitogen also involved in differentiation processes in mammalian cells.;Benito;Int J Biochem Cell Biol,1996

2. Insulin-like growth factor-I is an essential regulator of the differentiation of 3T3–L1 adipocytes.;Smith;J Biol Chem,1988

3. Adipose conversion of 3T3–L1 cells in a serum-free culture system depends on epidermal growth factor, insulin-like growth factor-I, corticosterone, and cyclic AMP.;Schmidt;J Biol Chem,1990

4. Understanding adipocyte differentiation.;Gregoire;Physiol Rev,1998

5. Molecular and cellular aspects of the insulin-like growth factor-I receptor.;LeRoith;Endocr Rev,1995

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