The Pregnane X Receptor: A Promiscuous Xenobiotic Receptor That Has Diverged during Evolution

Author:

Jones Stacey A.1,Moore Linda B.1,Shenk Jennifer L.1,Wisely G. Bruce1,Hamilton Geraldine A.2,McKee David D.1,Tomkinson Nicholas C. O.3,LeCluyse Edward L.2,Lambert Millard H.4,Willson Timothy M.3,Kliewer Steven A.1,Moore John T.1

Affiliation:

1. Departments of Molecular Endocrinology (S.A.J., L.B.M., J.L.S., G.B.W., D.D.M., S.A.K., J.T.M.), North Carolina 27709

2. Department of Drug Delivery and Disposition (G.A.H., E.L.L.) School of Pharmacy University of North Carolina at Chapel Hill Chapel Hill, North Carolina 27599

3. Medicinal Chemistry (N.C.O.T, T.M.W.), North Carolina 27709

4. Structural Chemistry (M.H.L) Glaxo Wellcome Inc. Research and Development Research Triangle Park, North Carolina 27709

Publisher

The Endocrine Society

Subject

Endocrinology,Molecular Biology,General Medicine

Reference44 articles.

1. The CYP3A family.;Maurel;Ioannides C (ed) Cytochromes P450: Metabolic and Toxicological Aspects.,1996

2. Regulation of the glucocorticoid-inducible cytochromes P450.;Guzelian;Microsomes and Drug Oxidations.,1988

3. Regulation of phenobarbital-inducible cytochrome P450 2B1/2 mRNA by lovastatin and oxysterols in primary cultures of adult rat hepatocytes.;Kocarek;Toxicol Appl Pharmacol,1993

4. Comparative analysis of cytochrome P4503A induction in primary cultures of rat, rabbit, and human hepatocyes.;Kocarek;Drug Met Dispos,1995

5. Trans-species gene transfer for analysis of glucocorticoid-inducible transcriptional activation of transiently expressed human CYP3A4 and rabbit CYP3A6 in primary cultures of adult rat and rabbit hepatocytes.;Barwick;Mol Pharmacol,1996

Cited by 320 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3