Significance of Mutations in the Androgen Receptor Gene in Males with Idiopathic Infertility1

Author:

Hiort Olaf1,Holterhus Paul-Martin1,Horter Thorsten2,Schulze Wolfgang3,Kremke Britta1,Bals-Pratsch Monika4,Sinnecker Gernot H. G.2,Kruse Klaus1

Affiliation:

1. Departments of Pediatrics, Medical University of Lübeck (O.H., P.-M.H., B.K., K.K.)

2. City Hospital Wolfsburg (G.H.G.S.), Children’s Hospital Hamburg-Altona (T.H.)

3. Department of Andrology (W.S.), University Hospital Hamburg-Eppendorf

4. and Department of Obstetrics and Gynecology (M.B.P.), Medical University of Lübeck, Germany

Publisher

The Endocrine Society

Subject

Biochemistry, medical,Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism

Reference31 articles.

1. The clinical and molecular spectrum of androgen insensitivity.;Hiort;Am J Med Genet,1996

2. Androgen insensitivity as a cause of infertility in otherwise normal men.;Aiman;N Engl J Med,1979

3. Long polyglutamine tracts in the androgen receptor are associated with reduced trans-activation, impaired sperm production, and male infertility.;Tut;J Clin Endocrinol Metab,1997

4. Linkage between male infertility and trinucleotide repeat expansion in the androgen-receptor gene.;Dowsing;Lancet,1999

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