Melanocortin-4 Receptor Signaling Is Required for Weight Loss after Gastric Bypass Surgery

Author:

Hatoum Ida J.12,Stylopoulos Nicholas12,Vanhoose Amanda M.3,Boyd Kelli L.4,Yin Deng Ping56,Ellacott Kate L. J.36,Ma Lian Li6,Blaszczyk Kasia7,Keogh Julia M.4,Cone Roger D.3,Farooqi I. Sadaf4,Kaplan Lee M.12

Affiliation:

1. Obesity, Metabolism, and Nutrition Institute and Gastrointestinal Unit (I.J.H., N.S., L.M.K.), Massachusetts General Hospital, Boston, Massachusetts 02129

2. Department of Medicine (I.J.H., N.S., L.M.K.), Harvard Medical School, Boston, Massachusetts 02115

3. Departments of Molecular Physiology and Biophysics (A.M.V., K.L.J.E., R.D.C.), Nashville, Tennessee 37232

4. University of Cambridge Metabolic Research Laboratories (K.L.B., J.M.K., I.S.F.), Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge DB2 2QQ, United Kingdom

5. Surgery (D.P.Y.), Nashville, Tennessee 37232

6. Vanderbilt Mouse Metabolic Phenotyping Center (D.P.Y., K.L.J.E., L.L.M.), Vanderbilt University School of Medicine, Nashville, Tennessee 37232

7. Pathology, Microbiology, and Immunology (K.B.), Nashville, Tennessee 37232

Publisher

The Endocrine Society

Subject

Biochemistry (medical),Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism

Reference39 articles.

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2. Increases in morbid obesity in the USA: 2000–2005.;Sturm;Public Health,2007

3. The medical care costs of obesity: an instrumental variables approach.;Cawley;J Health Econ,2012

4. Long-term effects of a lifestyle intervention on weight and cardiovascular risk factors in individuals with type 2 diabetes mellitus: four-year results of the Look AHEAD trial.;Wing;Arch Intern Med,2010

5. Comparison of the Atkins, Zone, Ornish, and LEARN diets for change in weight and related risk factors among overweight premenopausal women: the A TO Z Weight Loss Study: a randomized trial.;Gardner;JAMA,2007

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