Mutation and Gene Copy Number Analyses of Six Pituitary Transcription Factor Genes in 71 Patients with Combined Pituitary Hormone Deficiency: Identification of a Single Patient withLHX4Deletion-Reference-Cited by-同舟云学术

Mutation and Gene Copy Number Analyses of Six Pituitary Transcription Factor Genes in 71 Patients with Combined Pituitary Hormone Deficiency: Identification of a Single Patient withLHX4Deletion

Published:2010-08-01 Issue:8 Volume:95 Page:4043-4047
ISSN:0021-972X
Container-title:The Journal of Clinical Endocrinology & Metabolism
language:en
Short-container-title:

Author:

Dateki Sumito¹²,Fukami Maki¹,Uematsu Ayumi³,Kaji Masayuki³,Iso Manami¹,Ono Makoto⁴,Mizota Michiyo⁵,Yokoya Susumu⁶,Motomura Katsuaki²,Kinoshita Eiichi²,Moriuchi Hiroyuki²,Ogata Tsutomu¹

Affiliation:

1. Department of Endocrinology and Metabolism (S.D., M.F., M.I., T.O.), National Research Institute for Child Health and Development, Tokyo 157-8535, Japan;

2. Department of Pediatrics (S.D., K.M., E.K., H.M.), Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8501, Japan;

3. Division of Endocrinology and Metabolism (A.U., M.K), Shizuoka Children’s Hospital, Shizuoka 232-8555, Japan;

4. Department of Pediatrics and Developmental Biology (M.O.), Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences, Tokyo 113-8519, Japan;

5. Department of Pediatrics (M.M.), Faculty of Medicine, Kagoshima University, Kagoshima 890-8544, Japan;

6. Department of Medical Subspecialties (S.Y.), National Children’s Medical Center, Tokyo 157-8535, Japan

Publisher

The Endocrine Society

Subject

Biochemistry, medical,Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism

Link

http://academic.oup.com/jcem/article-pdf/95/8/4043/9069817/jcem4043.pdf

Reference18 articles.

1. Molecular basis of combined pituitary hormone deficiencies.;Cohen;Endocr Rev,2002

2. Genetic regulation of pituitary gland development in human and mouse.;Kelberman;Endocr Rev,2009

3. Heterozygous orthodenticle homeobox 2 mutations are associated with variable pituitary phenotype.;Dateki;J Clin Endocrinol Metab,2010