Neuron-Restricted Expression of the Rat Gonadotropin-Releasing Hormone Gene Is Conferred by a Cell-Specific Protein Complex that Binds Repeated CAATT Elements

Author:

Kelley Carolyn G.1,Givens Marjory L.1,Rave-Harel Naama1,Nelson Shelley B.1,Anderson Scott1,Mellon Pamela L.1

Affiliation:

1. Departments of Reproductive Medicine and Neuroscience, Center for the Study of Reproductive Biology and Disease, University of California, San Diego, La Jolla, California 92093-0674

Publisher

The Endocrine Society

Subject

Endocrinology,Molecular Biology,General Medicine

Reference32 articles.

1. Evidence that cells expressing luteinizing hormone-releasing hormone mRNA in the mouse are derived from progenitor cells in the olfactory placode.;Wray;Proc Natl Acad Sci USA,1989

2. Immortalization of hypothalamic GnRH neurons by genetically targeted tumorigenesis.;Mellon;Neuron,1990

3. A neuron-specific enhancer targets expression of the gonadotropin-releasing hormone gene to hypothalamic neurosecretory neurons.;Whyte;Mol Endocrinol,1995

4. Regulation of GnRH transcription by protein kinase C is mediated by evolutionarily conserved, promoter-proximal elements.;Eraly;Mol Endocrinol,1995

5. The Otx2 homeoprotein regulates expression from the gonadotropin-releasing hormone proximal promoter.;Kelley;Mol Endocrinol,2000

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