Primary Medical Therapy for Acromegaly: An Open, Prospective, Multicenter Study of the Effects of Subcutaneous and Intramuscular Slow-Release Octreotide on Growth Hormone, Insulin-Like Growth Factor-I, and Tumor Size

Author:

Bevan J. S.1,Atkin S. L.2,Atkinson A. B.3,Bouloux P.-M.4,Hanna F.5,Harris P. E.6,James R. A.7,McConnell M.3,Roberts G. A.6,Scanlon M. F.5,Stewart P. M.8,Teasdale E.9,Turner H. E.10,Wass J. A. H.10,Wardlaw J. M.11

Affiliation:

1. Department of Endocrinology, Aberdeen Royal Infirmary (J.S.B.), Aberdeen, United Kingdom AB25 2ZN;

2. Department of Endocrinology, Hull Royal Infirmary (S.L.A.), Hull, United Kingdom HU3 3KZ;

3. Department of Endocrinology, Royal Victoria Hospital (A.B.A., M.M.), Belfast, United Kingdom BT12 6BA;

4. Department of Endocrinology, Royal Free Hospital (P.-M.B.), London, United Kingdom NW3 2QQ;

5. Department of Endocrinology, University Hospital of Wales (F.H., M.F.S.), Cardiff, United Kingdom CF4 4XN;

6. Department of Endocrinology, Kings’ College Hospital (P.E.H., G.A.R.), London, United Kingdom SE5 9RS;

7. Department of Endocrinology, Royal Victoria Infirmary (R.A.J.), Newcastle-upon-Tyne, United Kingdom NE1 4LP;

8. Department of Endocrinology, Queen Elizabeth Hospital (P.M.S.), Birmingham, United Kingdom B15 2TH;

9. Department of Neuroradiology, Southern General Hospital (E.T.), Glasgow, United Kingdom G51 4TF;

10. Department of Endocrinology, Radcliffe Infirmary (H.E.T., J.A.H.W.), Oxford, United Kingdom OX2 6HE;

11. Department of Neuroradiology, Western General Hospital (J.M.W.), Edinburgh, United Kingdom EH4 2XU

Publisher

The Endocrine Society

Subject

Biochemistry (medical),Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism

Reference22 articles.

1. Current therapy for acromegaly.;Stewart;Trends Endocrinol Metab,2000

2. Long-term mortality after transsphenoidal surgery and adjunctive therapy for acromegaly.;Swearingen;J Clin Endocrinol Metab,1998

3. Outcome of transphenoidal surgery for acromegaly and its relationship to surgical experience.;Ahmed;Clin Endocrinol (Oxf),1999

4. Effects of pre-operative octreotide treatment on different subtypes of 90 growth hormone secreting pituitary adenomas and outcome in one surgical centre.;Abe;Eur J Endocrinol,2001

5. Outcome of transsphenoidal surgery for acromegaly using strict criteria for surgical cure.;Sheaves;Clin Endocrinol (Oxf),1996

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