Feedback on LH in Testosterone-Clamped Men Depends on the Mode of Testosterone Administration and Body Composition

Author:

Roelfsema Ferdinand1,Yang Rebecca J2,Liu Peter Y23,Takahashi Paul Y4,Veldhuis Johannes D2ORCID

Affiliation:

1. Department of Internal Medicine, Section Endocrinology and Metabolism, Leiden University Medical Center, Leiden, Netherlands

2. Endocrine Research Unit, Mayo School of Graduate Medical Education, Center for Translational Science Activities, Mayo Clinic, Rochester, Minnesota

3. Division of Endocrinology, Department of Medicine, David Geffen School of Medicine at University of California Los Angeles, Harbor-University of California Los Angeles Medical Center, and Los Angeles Biomedical Research Institute, Los Angeles, California

4. Department of Primary Care Internal Medicine, Mayo Clinic, Rochester, Minnesota

Funder

National Institutes of Health

National Center for Advancing Translational Sciences

National Institute of Standards and Technology

Publisher

The Endocrine Society

Subject

Endocrinology, Diabetes and Metabolism

Reference46 articles.

1. Definition of the hypothalamic GnRH pulse generator in mice;Clarkson;Proc Natl Acad Sci USA,2017

2. Specific linkages among luteinizing hormone, follicle-stimulating hormone, and testosterone release in the peripheral blood and human spermatic vein: evidence for both positive (feed-forward) and negative (feedback) within-axis regulation;Foresta;J Clin Endocrinol Metab,1997

3. Sex steroid control of gonadotropin secretion in the human male. I. Effects of testosterone administration in normal and gonadotropin-releasing hormone-deficient men;Finkelstein;J Clin Endocrinol Metab,1991

4. Neuroendocrine mechanisms by which selective Leydig cell castration unleashes increased pulsatile LH release;Veldhuis;Am J Physiol,1997

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