Idoxifene: A Novel Selective Estrogen Receptor Modulator Prevents Bone Loss and Lowers Cholesterol Levels in Ovariectomized Rats and Decreases Uterine Weight in Intact Rats

Author:

Nuttall Mark E.,Bradbeer Jeremy N.,Stroup George B.,Nadeau Daniel P.,Hoffman Sandra J.,Zhao Hugh,Rehm Sabine1,Gowen Maxine

Affiliation:

1. Departments of Bone and Cartilage Biology, and Safety Assessment (SR), SmithKline Beecham Pharmaceuticals, King of Prussia, Pennsylvania 19406

Publisher

The Endocrine Society

Subject

Endocrinology

Reference46 articles.

1. Sex steroids in the pathogenesis and prevention of osteoporosis;Lindsay,1988

2. Estrogens in the prevention and treatment of postmenopausal osteoporosis: a review.;Barzel;Am J Med,1988

3. The epidemiology of coronary heart disease and estrogen replacement in postmenopausal women.;Grodstein;Prog Cardiovasc Dis,1995

4. HRT: an analysis of benefits, risks and costs.;Daley;Br Med Bull,1992

5. Osteoporosis: problems for the future.;Hosking,1990

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