Insulin, But Not Glucose Lowering Corrects the Hyperglucagonemia and Increased Proglucagon Messenger Ribonucleic Acid Levels Observed in Insulinopenic Diabetes**This work was supported by the Swiss National Fund (Grant 32–46816.96 to J.P. and Grant 32–34086.95 to P.M.), the Institute for Human Genetics and Biochemistry, the Nägeli Wolfermann Foundation, the Horten Foundation, and the Juvenile Diabetes Foundation International (Grant 197124).

Author:

Dumonteil Eric1,Magnan Christophe2,Ritz-Laser Beate1,Meda Paolo3,Dussoix Philippe1,Gilbert Marc2,Ktorza Alain2,Philippe Jacques1

Affiliation:

1. Unité de Diabétologie Clinique, Department of Medicine (E.D., B.R.-L., P.D., J.P.), Centre Médical Universitaire, 1211 Geneva 4, Switzerland;

2. Laboratoire de Physiopathologie de la Nutrition, Centre National de la Recherche Scientifique, URA 307, Université Paris 7-Denis Diderot (C.M., M.G., A.K.), 75005 Paris, France

3. Department of Morphology (P.M.), Centre Médical Universitaire, 1211 Geneva 4, Switzerland;

Publisher

The Endocrine Society

Subject

Endocrinology

Reference31 articles.

1. Structure and pancreatic expression of the insulin and glucagon genes.;Philippe;Endocr Rev,1991

2. Glucagon and its family revisited.;Lefèbvre;Diabetes Care,1995

3. Glucagon and diabetes. In: Lefèbvre PJ (ed) Handbook of Experimental Pharmacology.;Lefèbvre;Springer-Verlag, Berlin and Heidelberg, vol,1996

4. Correction of hyperglycemia with phloridzin restores the glucagon response to glucose in insulin-deficient dogs: implications for human diabetes.;Starke;Proc Natl Acad Sci USA,1985

5. Relationship of glucagon suppression by insulin and somatostatin to the ambient glucose concentration.;Starke;J Clin Invest,1987

Cited by 15 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3