Evidence That Gonadotropin-Releasing Hormone Stimulates Gene Expression and Levels of Active Nitric Oxide Synthase Type I in Pituitary Gonadotrophs, a Process Altered by Desensitization and, Indirectly, by Gonadal Steroids*

Author:

Garrel Ghislaine1,Lerrant Yannick12,Siriostis Céline1,Bérault Annette1,Magre Solange3,Bouchaud Claude4,Counis Raymond1

Affiliation:

1. Endocrinologie Cellulaire et Moléculaire de la Reproduction (G.G., Y.L., C.S., A.B., R.C.), Université Pierre & Marie Curie, CNRS-URA 1449, Paris, France

2. Université Française du Pacifique, Tahiti (Y.L.), Université Pierre & Marie Curie, CNRS-URA 1449, Paris, France

3. Différenciation de la Gonade (S.M.), Université Pierre & Marie Curie, CNRS-URA 1449, Paris, France

4. Institut des Neurosciences (C.B.), Université Pierre & Marie Curie, CNRS-URA 1488, Paris, France

Publisher

The Endocrine Society

Subject

Endocrinology

Reference44 articles.

1. Molecular biology of the pituitary gonadotropins.;Gharib;Endocr Rev,1990

2. Regulation of pituitary gonadotropin gene expression. Outline of intracellular signaling pathways.;Counis;Trends Endocrinol Metab,1991

3. Mandatory neuropeptide-steroid signaling for the preovulatory luteinizing hormone-releasing hormone discharge.;Kalra;Endocr Rev,1993

4. Gonadotropin-releasing hormone receptors: structure and signal transduction pathways.;Stojilkovic;Endocr Rev,1994

5. GnRH action in gonadotropes. Cross-talk between phosphoinositidase C and adenylyl cyclase mediated signaling pathways.;McArdle;Trends Endocrinol Metab,1996

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