Altered Selectivity of Parathyroid Hormone (PTH) and PTH-Related Protein (PTHrP) for Distinct Conformations of the PTH/PTHrP Receptor-Reference-Cited by-同舟云学术

Altered Selectivity of Parathyroid Hormone (PTH) and PTH-Related Protein (PTHrP) for Distinct Conformations of the PTH/PTHrP Receptor

Published:2008-01-01 Issue:1 Volume:22 Page:156-166
ISSN:0888-8809
Container-title:Molecular Endocrinology
language:en
Short-container-title:

Author:

Dean Thomas¹,Vilardaga Jean-Pierre²,Potts John T.¹,Gardella Thomas J.¹

Affiliation:

1. Endocrine Unit (T.D., J.-P.V., J.T.P., T.J.G.), Boston, Massachusetts 02114

2. Program in Membrane Biology (J.-P.V.), Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114

Publisher

The Endocrine Society

Subject

Endocrinology,Molecular Biology,General Medicine

Link

http://academic.oup.com/mend/article-pdf/22/1/156/8937983/mend0156.pdf

Reference42 articles.

1. Teriparatide [human PTH(1–34)]: 2.5 years of experience on the use and safety of the drug for the treatment of osteoporosis.;Jr;J Bone Miner Res,2006

2. PTHrP and skeletal development.;Kronenberg;Ann NY Acad Sci,2006

3. Osteoblast-derived PTHrP is a potent endogenous bone anabolic agent that modifies the therapeutic efficacy of administered PTH 1–34.;Miao;J Clin Invest,2005

4. Osteoblast-derived PTHrP is a physiological regulator of bone formation.;Martin;J Clin Invest,2005

5. The bovine renal parathyroid hormone (PTH) receptor has equal affinity for two different amino acid sequences: the receptor binding domains of PTH and PTH-related protein are located within the 14–34 region.;Caulfield;Endocrinology,1990

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