Direct Luteinizing Hormone Action Triggers Adrenocortical Tumorigenesis in Castrated Mice Transgenic for The Murine Inhibinα -Subunit Promoter/Simian Virus 40 T-Antigen Fusion Gene

Author:

Rilianawati 1,Paukku Tommi1,Kero Jukka1,Zhang Fu-Ping1,Rahman Nafis1,Kananen Kirsi1,Huhtaniemi Ilpo1

Affiliation:

1. Department of Physiology University of Turku 20520 Turku, Finland

Publisher

The Endocrine Society

Subject

Endocrinology,Molecular Biology,General Medicine

Reference43 articles.

1. Gonadal tumorigenesis in transgenic mice bearing the mouse inhibin α-subunit promoter/Simian virus T-antigen fusion gene: characterization of ovarian tumors and establishment of gonadotropin-responsive granulosa cell lines.;Kananen;Mol Endocrinol,1995

2. The mouse inhibin α-subunit promoter directs SV40 T-antigen to Leydig cells of transgenic mice.;Kananen;Mol Cell Endocrinol,1996

3. Gonadectomy permits adrenocortical tumorigenesis in mice transgenic for the mouse inhibin α-subunit promoter/Simian Virus 40 T-antigen fusion gene: evidence for negative autoregulation of the inhibin α-subunit gene.;Kananen;Mol Endocrinol,1996

4. Suppression of gonadotropins inhibits gonadal tumorigenesis in mice transgenic for the mouse inhibin α-subunit promoter/SV40 T-antigen fusion gene.;Kananen;Endocrinology,1997

5. α-Inhibin is a tumour-suppressor gene with a gonadal specificity in mice.;Matzuk;Nature,1992

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