Dominant Negative Variants of the SHP-2 Tyrosine Phosphatase Inhibit Prolactin Activation of Jak2 (Janus Kinase 2) and Induction of Stat5 (Signal Transducer and Activator of Transcription 5)-Dependent Transcription-Reference-Cited by-同舟云学术

Dominant Negative Variants of the SHP-2 Tyrosine Phosphatase Inhibit Prolactin Activation of Jak2 (Janus Kinase 2) and Induction of Stat5 (Signal Transducer and Activator of Transcription 5)-Dependent Transcription

Published:1998-04-01 Issue:4 Volume:12 Page:556-567
ISSN:0888-8809
Container-title:Molecular Endocrinology
language:en
Short-container-title:

Author:

Berchtold Susanne¹,Volarevic Sinisa²,Moriggl Richard¹,Mercep Mladen²,Groner Bernd¹

Affiliation:

1. Institute for Experimental Cancer Research (S.B., R.M., B.G.) Tumor Biology Center and Department of Biology University of Freiburg 79106 Freiburg, Germany

2. Novartis Inc. (S.V., M.M.) CH 4002 Basel, Switzerland

Publisher

The Endocrine Society

Subject

Endocrinology,Molecular Biology,General Medicine

Link

http://academic.oup.com/mend/article-pdf/12/4/556/10614406/mend0556.pdf

Reference63 articles.

1. Prolactin regulation of the β-casein expression and of a cytosolic 120-kd protein in a cloned mouse mammary epithelial cell line.;Ball;EMBO J,1988

2. Mammary gland factor activated by prolactin in mammary epithelial cells and acute-phase response factor activated by IL-6 in liver cells share DNA binding and transactivation potential.;Standke;Mol Endocrinol,1994

3. Prolactin induces phosphorylation of Tyr694 of Stat5 (MGF), a prerequisite for DNA binding and induction of transcription.;Gouilleux;EMBO J,1994

4. Interferon-regulatory factor 1 is an immediate-early gene under transcriptional regulation by prolactin in Nb2 cells.;Yu-Lee;Mol Cell Biol,1990

5. Identification of Jak protein tyrosine kinases as signaling molecules for prolactin. Functional analysis of prolactin receptor and prolactin-erythropoietin receptor chimera expressed in lymphoid cells.;Dusanter-Fourt;EMBO J,1994

Cited by 36 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. SHP2 inhibition displays efficacy as a monotherapy and in combination with JAK2 inhibition in preclinical models of myeloproliferative neoplasms;American Journal of Hematology;2024-03-05

2. Growth Factors, and Cytokines; Understanding the Role of Tyrosine Phosphatase SHP2 in Gametogenesis and Early Embryo Development;Cells;2020-07-29

3. Physiological Actions and Receptors;Prolactin Disorders;2019

4. Physiopathology, Diagnosis, and Treatment of Hyperprolactinemia;Endocrinology;2018

5. Physiopathology, Diagnosis, and Treatment of Hyperprolactinemia;Endocrinology;2017-11-29