A Novel Natural Mutation in the Thyroid Hormone Receptor Defines a Dual Functional Domain That Exchanges Nuclear Receptor Corepressors and Coactivators

Author:

Tagami Tetsuya1,Gu Wen-Xia1,Peairs Patricia T.2,West Brian L.3,Jameson J. Larry1

Affiliation:

1. Division of Endocrinology, Metabolism, and Molecular Medicine (T.T., W.-X.G., J.L.J) Northwestern University Medical School Chicago, Illinois 60611

2. The Baton Rouge Clinic (P.T.P.) Baton Rouge, Louisiana 70806

3. Metabolic Research Unit (B.L.W.) University of California at San Francisco San Francisco, California 94143

Publisher

The Endocrine Society

Subject

Endocrinology,Molecular Biology,General Medicine

Reference69 articles.

1. The syndromes of resistance to thyroid hormone.;Refetoff;Endocr Rev,1993

2. Syndrome of resistance to thyroid hormone: insights into thyroid hormone action.;Kopp;Proc Soc Exp Biol Med,1996

3. Mechanisms of thyroid hormone action;Jameson,1995

4. The nuclear receptor superfamily: the second decade.;Mangelsdorf;Cell,1995

5. Thyroid hormone aporeceptor represses T3-inducible promoters and blocks activity of the retinoic acid receptor.;Brent;New Biol,1989

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