Rescuing 3T3-L1 Adipocytes from Insulin Resistance Induced by Stimulation of Akt-Mammalian Target of Rapamycin/p70 S6 Kinase (S6K1) Pathway and Serine Phosphorylation of Insulin Receptor Substrate-1: Effect of Reduced Expression of p85α Subunit of Phosphatidylinositol 3-Kinase and S6K1 Kinase
Author:
Affiliation:
1. Research Service (R.A., J.W.L., R.H., B.D.), Department of Veterans Affairs University of Colorado Denver, Aurora, Colorado 80045
2. Department of Medicine (R.A., B.D.), University of Colorado Denver, Aurora, Colorado 80045
Publisher
The Endocrine Society
Subject
Endocrinology
Link
http://academic.oup.com/endo/article-pdf/150/3/1165/9001431/endo1165.pdf
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5. Inappropriate activation of the TSC/Rheb/mTOR/S6K cassette induces IRS1/2 depletion, insulin resistance, and cell survival deficiencies.;Shah;Curr Biol,2004
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