Infantile Hypophosphatasia: Transplantation Therapy Trial Using Bone Fragments and Cultured Osteoblasts

Author:

Cahill Richard A.1,Wenkert Deborah2,Perlman Sharon A.3,Steele Ann3,Coburn Stephen P.4,McAlister William H.5,Mumm Steven62,Whyte Michael P.62

Affiliation:

1. Pediatric Research Institute (R.A.C.), Cardinal Glennon Children’s Hospital, St. Louis, Missouri 63110

2. Center for Metabolic Bone Disease and Molecular Research (D.W., S.M., M.P.W.), Shriners Hospitals for Children, St. Louis, Missouri 63131

3. All Children’s Hospital (S.A.P., A.S.), University of South Florida, St. Petersburg, Florida 33713

4. Department of Chemistry (S.P.C.), Indiana University-Purdue University, Fort Wayne, Indiana 46805

5. Mallinckrodt Institute of Radiology (W.H.M.), Washington University School of Medicine at Barnes-Jewish Hospital, St. Louis, Missouri 63110

6. Washington University School of Medicine at St. Louis Children’s Hospital, and Division of Bone and Mineral Diseases (S.M., M.P.W.), Washington University School of Medicine at Barnes-Jewish Hospital, St. Louis, Missouri 63110

Publisher

The Endocrine Society

Subject

Biochemistry (medical),Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism

Reference71 articles.

1. Hypophosphatasia;Whyte;In: Scriver CR, Beaudet AL, Sly WS, Valle D, Childs B, Vogelstein B, eds. The metabolic and molecular bases of inherited disease. 8th ed. New York: McGraw-Hill;,2001

2. Hypophosphatasia and the role of alkaline phosphatase in skeletal mineralization.;Whyte;Endocr Rev,1994

3. Different missense mutations at the tissue-nonspecific alkaline phosphatase gene locus in autosomal recessively inherited forms of mild and severe hypophosphatasia.;Henthorn;Proc Natl Acad Sci USA,1992

4. Matrix vesicles in osteomalacic hypophosphatasia bone contain apatite-like mineral crystals.;Anderson;Am J Pathol,1997

5. Analysis of localization of mutated tissue-nonspecific alkaline phosphatase proteins associated with neonatal hypophosphatasia using green fluorescent protein chimeras.;Cai;J Clin Endocrinol Metab,1998

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