Mutations in theAryl Hydrocarbon Receptor Interacting ProteinGene Are Not Highly Prevalent among Subjects with Sporadic Pituitary Adenomas

Author:

Barlier Anne123,Vanbellinghen Jean-François4,Daly Adrian F.5,Silvy Monique2,Jaffrain-Rea Marie-Lise6,Trouillas Jacqueline7,Tamagno Gianluca5,Cazabat Laure8,Bours Vincent4,Brue Thierry13,Enjalbert Alain23,Beckers Albert5

Affiliation:

1. Department of Endocrinology (T.B., A.Ba.), Centre Hospitalier Universitaire Timone, 13385 Marseille Cedex 5, France

2. Laboratory of Biochemistry and Molecular Biology (M.S., A.E., A.Ba.), Centre Hospitalier Universitaire Conception, 13385 Marseille Cedex 5, France

3. Laboratoire Interactions Cellulaires Neuroendocriniennes (A.E., T.B., A.Ba.), Centre National de la Recherche Scientifique Unité Mixte de Recherche 6544, Institut Fédératif Jean Roche, Faculté de Médecine, Université de la Méditerranée, 13916 Marseille Cedex 20, France

4. Department of Molecular Genetics (J.-F.V., V.B.), Centre Hospitalier Universitaire de Liège, University of Liège, 4000 Liège, Belgium

5. Department of Endocrinology (A.F.D., G.T., A.Be.), Centre Hospitalier Universitaire de Liège, University of Liège, 4000 Liège, Belgium

6. Department of Experimental Medicine (M.-L.J.-R.), University of L’Aquila and Neuromed, Istituto di Ricovero e Cura a Carattere Scientifico, 86077 Pozzili, Italy

7. Laboratory of Histology and Molecular Embryology (J.T.), Institut National de la Santé et de la Recherche Médicale U433, Faculty of Medicine Lyon-RTH Laennec, 69372 Lyon Cedex 08, France

8. Service d’Endocrinologie (L.C.), Hôpital Cochin et Institut National de la Santé et de la Recherche Médicale U567, 75014 Paris, France

Publisher

The Endocrine Society

Subject

Biochemistry, medical,Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism

Reference18 articles.

1. Prognostic and therapeutic consequences of Gsα mutations in somatotroph adenomas.;Barlier;J Clin Endocrinol Metab,1998

2. GTPase inhibiting mutations activate the α chain of Gs and stimulate adenylyl cyclase in human pituitary tumors.;Landis;Nature,1989

3. Isolation and characterization of a pituitary tumor-transforming gene (PTTG).;Pei;Mol Endocrinol,1997

4. Hypermethylation of the promoter region is associated with the loss of MEG3 gene expression in human pituitary tumors.;Zhao;J Clin Endocrinol Metab,2005

5. Mutations of the MEN1 tumor suppressor gene in pituitary tumors.;Zhuang;Cancer Res,1997

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