B Lymphocyte Depletion with the Monoclonal Antibody Rituximab in Graves’ Disease: A Controlled Pilot Study

Author:

El Fassi Daniel12,Nielsen Claus H.2,Bonnema Steen J.1,Hasselbalch Hans C.3,Hegedüs Laszlo1

Affiliation:

1. Department of Endocrinology and Metabolism (D.E.F., S.J.B., L.H.), Odense University Hospital, 5000 Odense, Denmark

2. Institute for Inflammation Research (D.E.F., C.H.N.), Rigshospitalet National University Hospital, 2100 Copenhagen, Denmark

3. Department of Hematology (H.C.H.), Odense University Hospital, 5000 Odense, Denmark

Publisher

The Endocrine Society

Subject

Biochemistry (medical),Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism

Reference20 articles.

1. Graves’ disease.;Weetman;N Engl J Med,2000

2. Quality of life in patients with benign thyroid disorders. A review.;Watt;Eur J Endocrinol,2006

3. Antithyroid drugs.;Cooper;N Engl J Med,2005

4. Serum thyrotropin receptor antibodies concentrations in patients with Graves’ disease before, at the end of methimazole treatment, and after drug withdrawal: evidence that the activity of thyrotropin receptor antibody and/or thyroid response modify during the observation period.;Carella;Thyroid,2006

5. B-cell targeting in rheumatoid arthritis and other autoimmune diseases.;Edwards;Nat Rev Immunol,2006

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