Predictive Value of Serum Calcitonin Levels for Preoperative Diagnosis of Medullary Thyroid Carcinoma in a Cohort of 5817 Consecutive Patients with Thyroid Nodules

Author:

Costante Giuseppe1,Meringolo Domenico2,Durante Cosimo3,Bianchi Davide2,Nocera Maria4,Tumino Salvatore5,Crocetti Umberto6,Attard Marco7,Maranghi Marianna3,Torlontano Massimo6,Filetti Sebastiano3

Affiliation:

1. Dipartimento di Medicina Sperimentale e Clinica (G.C.), Università Magna Græcia, 88100 Catanzaro, Italy

2. Unità Operativa Semplice Dipartimentale di Endocrinologia (D.M., D.B.), Ospedale di Bentivoglio, 40010 Bologna, Italy

3. Dipartimento di Scienze Cliniche (C.D., M.M., S.F.), Università degli Studi di Roma La Sapienza, 00161 Rome, Italy

4. Divisione di Medicina Interna (M.N.), Ospedale S. Giovanni di Dio, 88900 Crotone, Italy

5. Dipartimento di Scienze Biomediche (S.T.), Università di Catania, 95123 Catania, Italy

6. Divisione di Endocrinologia (U.C., M.T.), Istituto di Ricovero e Cura a Carattere Scientifico, Casa Sollievo della Sofferenza, 71013 San Giovanni Rotondo, Italy

7. Divisione di Endocrinologia (M.A.), Ospedale Cervello, 90146 Palermo, Italy

Publisher

The Endocrine Society

Subject

Biochemistry, medical,Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism

Reference31 articles.

1. Preoperative calcitonin levels are predictive of tumor size and postoperative calcitonin normalization in medullary thyroid carcinoma.;Cohen;J Clin Endocrinol Metab,2000

2. Multiple endocrine neoplasia type 2;Russo;In: Tamburrano G, Casanueva FF, Baldelli R, eds. Update in neuroendocrinology. From basic research to clinical practice. Rome: Pubblicazioni Medico Scientifiche;,2004

3. Early diagnosis of medullary carcinoma of the thyroid by means of calcitonin assay.;Melvin;N Engl J Med,1971

4. The clinical course after definitive operation for medullary thyroid carcinoma.;Jackson;Surgery,1983

5. The importance of early diagnosis in patients with hereditary medullary thyroid carcinoma.;Wells Jr;Ann Surg,1982

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