Suppression of a Pituitary-Ovarian Axis by Chronic Oral Administration of a Novel Nonpeptide Gonadotropin-Releasing Hormone Antagonist, TAK-013, in Cynomolgus Monkeys
Author:
Affiliation:
1. Pharmaceutical Research Division (T.H., H.A., M.K., M.H., N.C., N.S., M.F.), Osaka 532-8686, Japan
2. Strategic Product Planning Department (S.F., M.F.), Takeda Chemical Industries, Ltd., Osaka 532-8686, Japan
Publisher
The Endocrine Society
Subject
Biochemistry, medical,Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism
Link
http://academic.oup.com/jcem/article-pdf/88/4/1697/9150067/jcem1697.pdf
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3. Rapid regression of uterine leiomyomas in response to daily administration of gonadotropin-releasing hormone antagonist.;Kettle;Fertil Steril,1993
4. Local tolerance, pharmacokinetics, and dynamics of ganirelix (Orgalutran) administration by Medi-Jector compared to conventional needle injections.;Oberye;Hum Reprod,2000
5. Pharmacokinetic and pharmacodynamic modeling of cetrorelix, an LH-RH antagonist, after subcutaneous administration in healthy premenopausal women.;Nagaraja;Clin Pharmacol Ther,2000
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