Regulatory Effects of Interleukin (IL)-1, Interferon-β, and IL-4 on the Production of IL-1 Receptor Antagonist by Human Adipose Tissue

Author:

Juge-Aubry Cristiana E.1,Somm Emmanuel1,Chicheportiche Rachel2,Burger Danielle2,Pernin Agnès1,Cuénod-Pittet Brigitte3,Quinodoz Pierre4,Giusti Vittorio5,Dayer Jean-Michel2,Meier Christoph A.1

Affiliation:

1. Endocrine Unit, Division of Endocrinology, Diabetes and Nutrition, Department of Internal Medicine (C.E.J.-A., E.S., A.P., C.A.M.), CH-1211 Geneva 14, Switzerland

2. Hans Wilsdorf Laboratory, Division of Immunology and Allergy, Department of Internal Medicine (R.C., D.B., J.-M.D.), CH-1211 Geneva 14, Switzerland

3. Plastic Reconstructive Surgery Unit, Division of Reconstructive Surgery, Department of Surgery (B.C.-P.), University Hospital, CH-1211 Geneva 14, Switzerland

4. La Tour Hospital (P.Q.), CH-1217 Meyrin, Switzerland

5. Division of Endocrinology, Diabetology and Metabolism, Department of Medicine (V.G.), University Hospital, CH-1011 Lausanne, Switzerland

Publisher

The Endocrine Society

Subject

Biochemistry, medical,Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism

Reference27 articles.

1. Omental and subcutaneous adipose tissues of obese subjects release interleukin-6: depot difference and regulation by glucocorticoid.;Fried;J Clin Endocrinol Metab,1998

2. Adipose expression of tumor necrosis factor-α: direct role in obesity-linked insulin resistance.;Hotamisligil;Science,1993

3. Adipose tissue is a major source of interleukin-1 receptor antagonist: upregulation in obesity and inflammation.;Juge-Aubry;Diabetes,2003

4. Inflammation, obesity, stress and coronary heart disease: is interleukin-6 the link?;Yudkin;Atherosclerosis,2000

5. Elevated levels of interleukin 6 are reduced in serum and subcutaneous adipose tissue of obese women after weight loss.;Bastard;J Clin Endocrinol Metab,2000

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