Regulation of PTEN (Phosphatase and Tensin Homolog Deleted on Chromosome 10) Expression by Estradiol and Progesterone in Human Endometrium

Author:

Guzeloglu-Kayisli Ozlem12,Kayisli Umit A.13,Al-Rejjal Rafat1,Zheng Wenxin4,Luleci Guven2,Arici Aydin1

Affiliation:

1. Division of Reproductive Endocrinology, Departments of Obstetrics and Gynecology (O.G.-K., U.A.K., R.A.-R., A.A.), New Haven, Connecticut 06520-8063;

2. Departments of Medical Biology and Genetics (O.G.-K., G.L.), Antalya 07070, Turkey

3. Histology and Embryology (U.A.K.), School of Medicine, Akdeniz University, Antalya 07070, Turkey

4. Pathology (W.Z.), Yale University School of Medicine, New Haven, Connecticut 06520-8063;

Publisher

The Endocrine Society

Subject

Biochemistry, medical,Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism

Reference37 articles.

1. PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer.;Li;Science,1997

2. Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers.;Steck;Nat Genet,1997

3. TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor β.;Li;Cancer Res,1997

4. Mutational spectra of PTEN/MMAC1 gene: a tumor suppressor with lipid phosphatase activity.;Ali;J Natl Cancer Inst,1999

5. Mutations of the human PTEN gene.;Bonneau;Hum Mutat,2000

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