Immunodetection of 11β-Hydroxysteroid Dehydrogenase Type 2 in Human Mineralocorticoid Target Tissues: Evidence for Nuclear Localization*

Author:

Shimojo Masako,Ricketts Marie L.,Petrelli Massimiliano D.,Moradi Phillip,Johnson Gerald D.1,Bradwell A. R.1,Hewison Martin,Howie Alexander J.2,Stewart Paul M.

Affiliation:

1. Departments of Medicine, Immunology (G.D.J., A.R.B.), University of Birmingham, Queen Elizabeth Hospital, Edgbaston, Birmingham, United Kingdom B15 2TH

2. Pathology (A.J.H.), University of Birmingham, Queen Elizabeth Hospital, Edgbaston, Birmingham, United Kingdom B15 2TH

Publisher

The Endocrine Society

Subject

Endocrinology

Reference39 articles.

1. The human gene for 11β-hydroxysteroid dehydrogenase. Structure, tissue distribution, and chromosomal localization.;Tannin;J Biol Chem,1991

2. Human kidney 11β-hydroxysteroid dehydrogenase is a high affinity NAD+-dependent enzyme and differs from the cloned “type I” isoform.;Stewart;J Clin Endocrinol Metab,1994

3. Cloning and tissue distribution of the human 11β-hydroxysteroid dehydrogenase type 2 enzyme;Albiston;Mol Cell Endocrinol,1994

4. Cloning of human mineralocorticoid receptor complementary DNA: structural and functional kinship with the glucocorticoid receptor.;Arriza;Science,1998

5. Localisation of 11β-hydroxysteroid dehydrogenase-tissue specific protector of the mineralocorticoid receptor.;Edwards;Lancet,1988

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