Somatotropic and Gonadotropic Axes Linkages in Infancy, Childhood, and the Puberty-Adult Transition-Reference-Cited by-同舟云学术

Somatotropic and Gonadotropic Axes Linkages in Infancy, Childhood, and the Puberty-Adult Transition

Published:2006-04-01 Issue:2 Volume:27 Page:101-140
ISSN:0163-769X
Container-title:Endocrine Reviews
language:en
Short-container-title:

Author:

Veldhuis Johannes D.¹,Roemmich James N.²,Richmond Erick J.³,Bowers Cyril Y.⁴

Affiliation:

1. Endocrine Research Unit (J.D.V.), Department of Internal Medicine, Mayo Medical School, Mayo School of Graduate Medical Education, General Clinical Research Center, Mayo Clinic, Rochester, Minnesota 55905;

2. Department of Pediatrics (J.N.R.), State University of New York at Buffalo, Buffalo, New York 14214-3000;

3. Pediatric Endocrinology (E.J.R.), National Children’s Hospital, San Jose 1000, Costa Rica;

4. Division of Endocrinology and Metabolism (C.Y.B.), Department of Internal Medicine, Tulane University Medical Center, New Orleans, Louisiana 70112-2699

Abstract

Integrative neuroendocrine control of the gonadotropic and somatotropic axes in childhood, puberty, and young adulthood proceeds via multiple convergent and divergent pathways in the human and experimental animal. Emerging ensemble concepts are required to embody independent, parallel, and interacting mechanisms that subserve physiological adaptations and pathological disruption of reproduction and growth. Significant advances in systems biology will be needed to address these challenges.

Publisher

The Endocrine Society

Subject

Endocrinology,Endocrinology, Diabetes and Metabolism

Link

http://academic.oup.com/edrv/article-pdf/27/2/101/10335622/edrv0101.pdf

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