1. Biostatistics Center, Massachusetts General Hospital, Boston, MA 02114, USA
2. Department of Medicine, Harvard Medical School, Boston, MA 02115, USA
3. Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA
4. Division of Cardiology, Columbia University, New York, NY 10027, USA
5. Biostatistics and Epidemiology, University of Massachusetts, Amherst, MA 01003, USA
6. Division of General Internal Medicine, Massachusetts General Hospital, Boston, MA 02114, United States of America
7. Irving Institute for Clinical and Translational Research, Columbia University, New York, NY 10032, USA