Insulin Resistance and Adrenal Androgen Synthesis Viewed Through a Monogenic Lens
Author:
Affiliation:
1. Centre for Cardiovascular Science, The University of Edinburgh , Edinburgh EH16 4TJ , UK
2. MRC Human Genetics Unit, Institute of Genetics and Cancer, The University of Edinburgh , Edinburgh EH4 2XU , UK
Funder
Wellcome Trust
Publisher
The Endocrine Society
Subject
Biochemistry (medical),Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism
Link
https://academic.oup.com/jcem/advance-article-pdf/doi/10.1210/clinem/dgac475/45564519/dgac475.pdf
Reference8 articles.
1. A new dawn for androgens: novel lessons from 11-oxygenated C19 steroids;Pretorius;Mol Cell Endocrinol.,2017
2. DHEA, DHEAS and PCOS;Goodarzi;J Steroid Biochem Mol Biol.,2015
3. AKR1C3-mediated adipose androgen generation drives lipotoxicity in women with polycystic ovary syndrome;O’Reilly;J Clin Endocrinol Metab.,2017
4. 11-oxygenated C19 steroids are the predominant androgens in polycystic ovary syndrome;O’Reilly;J Clin Endocrinol Metab.,2017
5. Ovarian hyperandrogenism and response to gonadotropin-releasing hormone analogues in primary severe insulin resistance;Huang-Doran;J Clin Endocrinol Metab.,2021
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