Clinical and Molecular Features of Patients With Leptin and Leptin Receptor Deficiency: Lessons of 25 Years of Research-Reference-Cited by-同舟云学术

Clinical and Molecular Features of Patients With Leptin and Leptin Receptor Deficiency: Lessons of 25 Years of Research

Published:2023-06-13 Issue:1 Volume:109 Page:e424-e425
ISSN:0021-972X
Container-title:The Journal of Clinical Endocrinology & Metabolism
language:en
Short-container-title:

Author:

Argente Jesús¹²³^ORCID,Tena-Sempere Manuel²⁴⁵^ORCID

Affiliation:

1. Department of Pediatrics & Pediatric Endocrinology, Universidad Autónoma de Madrid; University Hospital Niño Jesús, Instituto de Investigación Sanitaria La Princesa , 28009 Madrid , Spain

2. CIBER Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III , 28029 Madrid , Spain

3. IMDEA Food Institute , 28049 Madrid , Spain

4. Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC) , 14004 Córdoba , Spain

5. Department of Cell Biology, Physiology and Immunology, University of Córdoba , 14004 Córdoba , Spain

Publisher

The Endocrine Society

Subject

Biochemistry (medical),Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism

Link

https://academic.oup.com/jcem/advance-article-pdf/doi/10.1210/clinem/dgad353/50646206/dgad353.pdf

Reference8 articles.

1. Congenital leptin deficiency is associated with severe early-onset obesity in humans;Montague;Nature,1997

2. A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction;Clément;Nature,1998

3. A leptin missense mutation associated with hypogonadism and morbid obesity;Strobel;Nat Genet,1998

4. Clinical and molecular genetic spectrum of congenital deficiency of the leptin receptor;Farooqi;N Engl J Med,2007

5. A national multicenter study of leptin and leptin receptor deficiency and systematic review;Besci;J Clin Endocrinol Metab,2023