1. Department of Diabetes, Endocrinology and Metabolism and Department of Rheumatology and Clinical Immunology, Gifu University Graduate School of Medicine , Gifu 501-1194 , Japan
2. Yutaka Seino Distinguished Center for Diabetes Research, Kansai Electric Power Medical Research Institute , Kyoto 604-8436 , Japan
3. Center for One Medicine Innovative Translational Research, Gifu University , Gifu 501-1194 , Japan