TRβ Agonism Induces Tumor Suppression and Enhances Drug Efficacy in Anaplastic Thyroid Cancer in Female Mice
Author:
Affiliation:
1. Department of Pharmacology, Larner College of Medicine, University of Vermont , Burlington, VT 05405 , USA
2. University of Vermont Cancer Center, University of Vermont , Burlington, VT 05405 , USA
Abstract
Funder
National Institutes of Health
National Cancer Institute
Publisher
The Endocrine Society
Subject
Endocrinology
Link
https://academic.oup.com/endo/advance-article-pdf/doi/10.1210/endocr/bqad135/51536342/bqad135.pdf
Reference50 articles.
1. Thyroid hormone receptors and cancer;Kim;Biochim Biophys Acta,2013
2. Thyroid hormone receptor beta induces a tumor-suppressive program in anaplastic thyroid cancer;Bolf;Mol Cancer Res,2020
3. Thyroid receptor: roles in cancer;Aranda;Trends Endocrinol Metab,2009
4. Inhibition of tumorigenesis by the thyroid hormone receptor beta in xenograft models;Kim;Thyroid,2014
5. Thyroid hormone inhibits hepatocellular carcinoma progression via induction of differentiation and metabolic reprogramming;Kowalik;J Hepatol,2020
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