Obesity and Postmenopausal Hormone Receptor-positive Breast Cancer: Epidemiology and Mechanisms

Author:

Zuo Qianying1,Band Shoham1,Kesavadas Mrinali1,Madak Erdogan Zeynep12345ORCID

Affiliation:

1. Department of Food Science and Human Nutrition, University of Illinois, Urbana-Champaign, Urbana, IL, USA

2. Cancer Center at Illinois, University of Illinois, Urbana-Champaign, Urbana, IL, USA

3. Institute for Genomic Biology, University of Illinois, Urbana-Champaign, Urbana, IL, USA

4. Division of Nutritional Sciences, University of Illinois, Urbana-Champaign, Urbana, IL, USA

5. Department of Biomedical and Translational Sciences, Carle Illinois, College of Medicine, University of Illinois, Urbana-Champaign, Urbana, IL, USA

Abstract

Abstract Obesity is a potential risk for several cancers, including postmenopausal, hormone dependent breast cancers. In this review, we summarize recent studies on the impact of obesity on postmenopausal women’s health and discuss several mechanisms that were proposed to increase the risk of breast carcinogenesis.

Publisher

The Endocrine Society

Subject

Endocrinology

Reference145 articles.

1. WHO recognition of the global obesity epidemic;James;Int J Obes (Lond).,2008

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