Selective Growth Inhibition in BRAF Mutant Thyroid Cancer by the Mitogen-Activated Protein Kinase Kinase 1/2 Inhibitor AZD6244-Reference-Cited by-同舟云学术

Selective Growth Inhibition in BRAF Mutant Thyroid Cancer by the Mitogen-Activated Protein Kinase Kinase 1/2 Inhibitor AZD6244

Published:2007-12-01 Issue:12 Volume:92 Page:4712-4718
ISSN:0021-972X
Container-title:The Journal of Clinical Endocrinology & Metabolism
language:en
Short-container-title:

Author:

Ball Douglas W.¹²,Jin Ning²,Rosen D. Marc²,Dackiw Alan³,Sidransky David⁴²,Xing Mingzhao¹²,Nelkin Barry D.²

Affiliation:

1. Division of Endocrinology and Metabolism (D.W.B., M.X.), Johns Hopkins University School of Medicine, Baltimore, Maryland 21287

2. Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (D.W.B., N.J., D.M.R., D.S., M.X., B.D.N.), Johns Hopkins University School of Medicine, Baltimore, Maryland 21287

3. Department of Surgery (A.D.), Johns Hopkins University School of Medicine, Baltimore, Maryland 21287

4. Department of Otolaryngology-Head and Neck Surgery (D.S.), Johns Hopkins University School of Medicine, Baltimore, Maryland 21287

Publisher

The Endocrine Society

Subject

Biochemistry (medical),Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism

Link

http://academic.oup.com/jcem/article-pdf/92/12/4712/9053346/jcem4712.pdf

Reference31 articles.

1. Challenging dogma in thyroid cancer molecular genetics—role of RET/PTC and BRAF in tumor initiation.;Fagin;J Clin Endocrinol Metab,2004

2. BRAF mutation in thyroid cancer.;Xing;Endocr Relat Cancer,2005

3. High prevalence of BRAF mutations in thyroid cancer: genetic evidence for constitutive activation of the RET/PTC-RAS-BRAF signaling pathway in papillary thyroid carcinoma.;Kimura;Cancer Res,2003

4. BRAF mutations and RET/PTC rearrangements are alternative events in the etiopathogenesis of PTC.;Soares;Oncogene,2003

5. Early occurrence of RASSF1A hypermethylation and its mutual exclusion with BRAF mutation in thyroid tumorigenesis.;Xing;Cancer Res,2004

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