The Heterogeneous Distribution of BRAF Mutation Supports the Independent Clonal Origin of Distinct Tumor Foci in Multifocal Papillary Thyroid Carcinoma

Author:

Giannini Riccardo1,Ugolini Clara1,Lupi Cristiana1,Proietti Agnese1,Elisei Rossella2,Salvatore Giuliana3,Berti Piero1,Materazzi Gabriele1,Miccoli Paolo1,Santoro Massimo3,Basolo Fulvio1

Affiliation:

1. Departments of Surgery (R.G., C.U., C.L., A.P., P.B., G.M., P.M., F.B.), University of Pisa, 56126 Pisa, Italy

2. Department of Endocrinology (R.E.), University of Pisa, 56126 Pisa, Italy

3. Dipartimento di Biologia e Patologia Cellulare e Molecolare (G.S., M.S.), University “Federico II”, c/o Istituto di Endocrinologia ed Oncologia Sperimentale del Consiglio Nazionale delle Ricerche, 80131 Naples, Italy

Publisher

The Endocrine Society

Subject

Biochemistry (medical),Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism

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