Dramatic Elevations of Interleukin-6 and Acute-Phase Reactants in Athletes Participating in the Ultradistance Foot Race Spartathlon: Severe Systemic Inflammation and Lipid and Lipoprotein Changes in Protracted Exercise

Author:

Margeli Alexandra1,Skenderi Katerina2,Tsironi Maria3,Hantzi Eugenia1,Matalas Antonia-Leda2,Vrettou Christina4,Kanavakis Emmanuel4,Chrousos George5,Papassotiriou Ioannis1

Affiliation:

1. Department of Clinical Biochemistry (A.M., E.H., I.P.), Aghia Sophia Children’s Hospital, GR 11527 Athens, Greece;

2. Laboratory of Nutrition and Clinical Dietetics (K.S., A.-L.M.), Harokopio University, GR 17671 Athens, Greece;

3. Department of Internal Medicine (M.T.), Sparta General Hospital, GR 23100 Sparta, Greece;

4. Medical Genetics (C.V., E.K.), Athens University, GR 11527 Athens, Greece;

5. First Department of Pediatrics (G.C.), Athens University, Medical School, GR 11527 Athens, Greece

Publisher

The Endocrine Society

Subject

Biochemistry (medical),Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism

Reference44 articles.

1. Special feature: exercise and cytokines.;Pedersen;Immunol Cell Biol,2000

2. Endogenous pyrogen activity in human plasma after exercise.;Cannon;Science,1983

3. Evidence that IL-6 is produced in skeletal muscle during intense long-term muscle activity.;Ostrowski;J Physiol (Lond),1998

4. The acute phase response and exercise: the ultramarathon as prototype exercise.;Fallon;Clin J Sport Med,2001

5. Exercise-induced muscle damage and inflammation: a review.;Pyne;Aust J Sci Med Sport,1994

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