Specificity and Regioselectivity of the Conjugation of Estradiol, Estrone, and Their Catecholestrogen and Methoxyestrogen Metabolites by Human Uridine Diphospho-glucuronosyltransferases Expressed in Endometrium-Reference-Cited by-同舟云学术

Specificity and Regioselectivity of the Conjugation of Estradiol, Estrone, and Their Catecholestrogen and Methoxyestrogen Metabolites by Human Uridine Diphospho-glucuronosyltransferases Expressed in Endometrium

Published:2004-10-01 Issue:10 Volume:89 Page:5222-5232
ISSN:0021-972X
Container-title:The Journal of Clinical Endocrinology & Metabolism
language:en
Short-container-title:

Author:

Lépine Johanie¹²,Bernard Olivier¹²,Plante Marie³,Têtu Bernard⁴,Pelletier Georges¹,Labrie Fernand¹,Bélanger Alain¹,Guillemette Chantal⁵¹²

Affiliation:

1. Department of Molecular Endocrinology and Oncology (J.L., O.B., G.P., F.L., A.B., C.G.), G1V 4G2 Québec, Canada

2. Laval University, Faculty of Pharmacy (J.L., O.B., C.G.), G1K 7P4 Québec, Canada

3. Faculty of Medicine, Gynecologic Oncology Service, Hôtel-Dieu de Québec (M.P.), G1K 7P4 Québec, Canada

4. Department of Pathology Hôtel-Dieu de Québec (B.T.), G1K 7P4 Québec, Canada

5. Canada Research Chair in Pharmacogenomics (C.G.); Centre de Recherche du Centre Hospitalier de l’Université Laval, G1V 4G2 Québec, Canada

Publisher

The Endocrine Society

Subject

Biochemistry, medical,Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism

Link

http://academic.oup.com/jcem/article-pdf/89/10/5222/10772088/jcem5222.pdf

Reference50 articles.

1. Elevated serum estradiol and testosterone concentrations are associated with a high risk for breast cancer. Study of Osteoporotic Fractures Research Group.;Cauley;Ann Intern Med,1999

2. Estrogens in the causation of breast, endometrial and ovarian cancers—evidence and hypotheses from epidemiological findings.;Persson;J Steroid Biochem Mol Biol,2000

3. Tissue-specific synthesis and oxidative metabolism of estrogens.;Jefcoate;J Natl Cancer Inst Monogr,2000

4. Functional role of estrogen metabolism in target cells: review and perspectives.;Zhu;Carcinogenesis,1998

5. CYP1B1 gene in endometrial cancer.;Sasaki;Mol Cell Endocrinol,2003

Cited by 164 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Glucuronidation of tizoxanide, an active metabolite of nitazoxanide, in liver and small intestine: Species differences in humans, monkeys, dogs, rats, and mice and responsible UDP-glucuronosyltransferase isoforms in humans;Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology;2024-09

2. Evaluation of Icotinib as a Potent and Selective Inhibitor of Aldehyde Oxidase for Reaction Phenotyping in Human Hepatocytes;Drug Metabolism and Disposition;2024-04-02

3. Similarities in Structure and Function of UDP-Glycosyltransferase Homologs from Human and Plants;International Journal of Molecular Sciences;2024-02-28

4. Detection of uridine diphosphate glucuronosyltransferase 1A1 for pancreatic cancer imaging and treatment via a “turn-on” fluorescent probe;The Analyst;2024

5. Quantitative analysis of the UDP‐glucuronosyltransferase transcriptome in human tissues;Pharmacology Research & Perspectives;2023-11-20