1. Departments of Nephrology (N.W., D.G.T., M.A., T.M., H.N., K.T., K.K.), Kumamoto 860-8556, Japan;
2. Biopharmaceutics (N.W., M.O.), Kumamoto University Graduate School of Medical and Pharmaceutical Sciences, Kumamoto 860-8556, Japan;
3. Department of Pediatrics, Sapporo Tokushukai Hospital (T.Ok., O.U.), Hokkaido 003-0021, Japan;
4. Department of Pediatrics, Fujita Health University School of Medicine (M.T.), Aichi 470-1192, Japan;
5. Department of Medicine, Kasukabe Shuwa Hospital (S.K.), Saitama 344-0038, Japan;
6. Department of Medicine, Kitasato Medical Center Hospital (Y.Y., H.S.), Saitama 364-0026, Japan;
7. Second Department of Internal Medicine (T.Od., Y.K.), Saitama 359-0042, Japan;
8. First Department of Physiology (H.M.), National Defense Medical College, Saitama 359-0042, Japan;
9. Department of Pharmacology and Toxicology, Kyorin University School of Medicine (M.H., H.E.), Tokyo 181-8611, Japan